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UK-NOTPR-1010 | April 2022

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Materials use and waste

Minimising consumption and environmental impacts

Developing most of our own manufacturing processes gives us the opportunity to minimise materials use, substitute unwanted substances and increase recycling. We rely on suppliers to deliver materials and handle waste sustainably. Environmental impacts from the end-use of our medicines are assessed and managed.

Our HSE approach

Our R&D and manufacturing activities are largely based on chemical synthesis, meaning we use considerable amounts of organic solvents and energy, generating waste and air emissions. We manage these environmental impacts through our integrated Health, Safety and Environment (HSE) approach. We define our overall priorities annually in our HSE Strategy and transform them into measurable targets and actions.

Green chemistry principles

We have applied green chemistry principles broadly for many years in Lundbeck, yielding several circular savings in our Active Pharmaceutical Ingredient (API) production, improving both yield and quality, and decreasing the use of reagents, catalysts, and solvents.

Best available technologies

We deploy the best available technologies when designing processes, technical utilities and facilities, to continuously improve our manufacturing processes. Where possible we use solvents with lower environmental impact and have increased our capabilities to recycle organic solvents in chemical production. This has allowed us to eliminate the need for thousands of tons of virgin materials and continue to save resources for production, transportation and waste management.

Continuous chemical production

We partner with universities to develop new working methods. For instance, by introducing continuous processing. Here the product is produced in a continuous flow in significantly smaller equipment than used in traditional batch processes where large reactors are filled, emptied and cleaned between each process step. This offers great benefits in raw material and energy usage.

Circular economy

By combining continuous production with recycling principles, we can create a circular economy, integrating different manufacturing processes and reusing materials across different processes. A number of results have demonstrated that circularity can deliver on both resource recycling and on reducing climate emissions. Thus, our Sustainability Strategy contains a circular economy aspiration to move away from the traditional linear ‘take-make-dispose’ manufacturing model to a more regenerative model. This is in line with the SDG 12 'Responsible Consumption and Production'.

 

There is an interest within the pharmaceutical industry to increase what can be recycled and reused in packaging materials. This is being pursued at the association level in close dialogue with relevant health authorities.

Water usage

Access to clean water resources is a growing global challenge. We work continuously to reduce our consumption of water and wastewater and have significantly done so over many years. Our savings on water consumption are due to technological improvements and various optimization activities on our production sites. We continuously map our water consumption to identify even more reduction potentials.   

 

The mapping showed that the discharge of purified water holds significant reduction potential and we will focus our efforts here in the coming years. As per World Resources Institute classifications, our research and production facilities are in low or low-medium areas of water availability. We carefully manage three areas in this regard: Water usage, wastewater and discharge of chemical residues into aquatic ecosystems. We ensure that water usage and wastewater emissions do not diminish the supply of clean water or degrade water quality. 

Pharmaceutical residues

We acknowledge stakeholder concerns about pharmaceutical residues in the environment. These mainly come from patients’ excretion of medicines taken to treat or prevent a disease. We test the environmental effects of new medicinal products and design processes with the least possible environmental impact.

 

We pursue approaches that balance healthcare needs and environmental considerations in line with EFPIA’s Eco-Pharmaco-Stewardship Initiative to minimise pharmaceuticals in the environment and UN Sustainability Development Goal 12 on responsible consumption and production. Read more about the EFPIA Eco-Pharmaco-Stweardship Initiative

Biodiversity

We do not operate in areas of high biodiversity value. Nor do we source natural resources from suppliers operating under a biodiversity policy or certification scheme e.g. The Forest Stewardship Council (FSC). However, Lundbeck takes biodiversity seriously and we seek to reduce our environmental impact by performing risk assessments, optimise processes and use the least harmful substances in our production.

Facts on ISO 14001 and ISO 45001

1

Lundbeck manages our health and safety through our integrated HSE system that is certified according to ISO 14001 and ISO 45001. ISO 14001 and ISO 45001 are international standards setting the requirements for Environment and Health & Safety Management Systems respectively. The standards can be applied to one system to enable businesses to identify and control all relevant impacts and hazards resulting from normal operations and abnormal situations and improve performance.

2

The system consists of written procedures and annual performance targets, communicated and integrated into daily operations via training. Compliance and improvements are evaluated by internal and external auditors and the business’ senior management reviews the overall system performance annually. 

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