Scientific Publications by Lundbeck employees

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The following research papers and other scientific publications were co-authored by members of the Lundbeck staff from 2000 to date.

For more information, please click here to access the Lundbeck Clinical Trial Registry.
 

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Publication title Author Source Drug Year
Gauge-origin independent magnetizabilities from hybrid quantum mechanics/molecular mechanics models: Theory and applications to liquid water Aidas K, Kongsted J, Nielsen CB, Mikkelsen KV, Christiansen O, Ruud K Chemical Physics Letters 2007;442(4-6):322-328 - 2007
A comparative study of the efficacy of acute and continuation treatment with escitalopram versus duloxetine in patients with major depressive disorder Wade A, Gembert K, Florea I Current Medical Research and Opinion 2007;23(7):1605-1614 Citalopram; Escitalopram 2007
Discontinuation symptoms in depression and anxiety disorders Baldwin DS, Montgomery SA, Nil R, Lader M International Journal of Neuropsychopharmacology 2007;10(1):73-84 Escitalopram 2007
Allosteric modulation of the effect of escitalopram, paroxetine and fluoxetine: in-vitro and in-vivo studies El Mansari M, Wiborg O, Mnie-Filali O, Benturquia N, Sanchez C, Haddjeri N International Journal of Neuropsychopharmacology 2007;10(1):31-40 Citalopram; Escitalopram 2007
Escitalopram in the treatment of anxiety symptoms associated with depression Bandelow B, Andersen HF, Dolberg OT Depression and anxiety 2007;24(1):53-61 Citalopram; Escitalopram 2007
An integrated microdialysis rat model for multiple pharmacokinetic/pharmacodynamic investigations of serotonergic agents Bundgaard C, Jorgensen M, Mork A Journal of Pharmacological and Toxicological Methods 2007;55(2):214-223 Citalopram; Escitalopram 2007
A prospective study of escitalopram in the treatment of major depressive episodes in the presence or absence of anxiety Olie JP, Tonnoir B, Menard F, Galinowski A Depression and anxiety 2007;24(5):318-324 Escitalopram 2007
Escitalopram and citalopram: The unexpected role of the R-enantiomer Jacquot C, David DJ, Gardier AM, Sanchez C Encephale 2007;33(2):179-187 Citalopram; Escitalopram 2007
Inactivation as a New Regulatory Mechanism for Neuronal Kv7 Channels Jensen HSl, Grunnet M, Olesen SP Biophysical Journal 2007;92(8):2747-2756 - 2007
Nuclear magnetic shielding constants of liquid water: Insights from hybrid quantum mechanics/molecular mechanics models Kongsted J, Nielsen CB, Mikkelsen KV, Christiansen O, Ruud K Journal of chemical physics 2007;126(3):034510-1 - 034510-8 - 2007
The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophrenia Wolinsky TD, Swanson CJ, Smith KE, Zhong H, Borowsky B, Seeman P, Branchek T, Gerald CP Genes Brain and Behavior 2007;6(7):628-639 - 2007
Pharmacokinetic/Pharmacodynamic feedback modelling of the functional corticosterone response in rats after acute treatment with escitalopram Bundgaard C, Larsen F, Jorgensen M, Mork A Basic and clinical pharmacology and toxicology 2007;100(3):182-189 Citalopram; Escitalopram 2007
Synthesis and preliminary pharmacological evaluation of the four stereoisomers of (2S)-2-(2'-phosphono-3'-phenylcyclopropyl)glycine, the first class of 3'-substituted transC1'-2'-2-(2'-phosphonocyclopropyl) glycines Marinozzi M, Serpi M, Amori L, Gavilan Diaz M, Costantino G, Meyer U, Flor PJ, Gasparini F, Heckendorn R, Kuhn R, Giorgi G, Brunsgaard Hermit M, Thomsen C, Pellicciari R Bioorganic and Medicinal Chemistry 2007;15(9):3161-3170 - 2007
Escitalopram in obsessive-compulsive disorder: A randomized, placebo-controlled, paroxetine-referenced, fixed-dose, 24-week study Stein DJ, Andersen EW, Tonnoir B, Fineberg N Current Medical Research and Opinion 2007;23(4):701-711 Citalopram; Escitalopram 2007
Safety and Efficacy of Oral Escitalopram as Continuation Treatment of Intravenous Citalopram in Patients with Major Depressive Disorder Schmitt L, Tonnoir B, Arbus C Neuropsychobiology 2007;54(4):201-207 Citalopram; Escitalopram 2007
The potential therapeutic use of phosphodiesterase 10 inhibitors Kehler J, Ritzen A, Greve DR Expert Opinion on Therapeutic Patents 2007;17(2):147-158 - 2007
Novel 5-Substituted 1-Pyrazolol Analogues of Ibotenic Acid: Synthesis and Pharmacology at Glutamate Receptors Jorgensen CG, Brauner-Osborne H, Nielsen B, Kehler J, Clausen RP, Krogsgaard-Larsen P, Madsen U Bioorganic and Medicinal Chemistry 2007. Article in Press, Accepted Manuscript: 3 March 2007 - 2007
Escitalopram in major depressive disorder: Clinical benefits and cost effectiveness versus citalopram Lancon C, Verpillat P, Annemans L, Despiegel N, Francois C International Journal of Psychiatry in Clinical Practice 2007;11(1):44-52 Citalopram; Escitalopram 2007
Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives Villa P, Van Beek J, Larsen AK, Gerwien J, Christensen S, Cerami A, Brines M, Leist M, Ghezzi P, Torup L Journal of Cerebral Blood Flow and Metabolism 2007;27(3):552-563 - 2007
A Common Reference Framework for Analyzing/Comparing Proteins and Ligands. Fingerprints for Ligands And Proteins (FLAP): Theory and Application Baroni M, Cruciani G, Sciabola S, Perruccio F, Mason JS Journal of Chemical Information and Modeling 2007;47(2):279-294 - 2007
Nanoporous magnesium aluminometasilicate tablets for precise, controlled, and continuous dosing of chemical reagents and catalysts: applications in parallel solution-phase synthesis Ruhland T, Nielsen SD, Holm P, Christensen CH Journal of Combinatorial Chemistry 2007;9(2):301-305 - 2007
4-Aryl-5-(4-Piperidyl)-3-Isoxazolol GABA(A) Antagonists: Synthesis, Pharmacology, and Structure-Activity Relationships Frolund B, Jensen LS, Storustovu SI, Stensbol TB, Ebert B, Kehler J, Krogsgaard-Larsen P, Liljefors T Journal of Medicinal Chemistry 2007;50(8):1988-1992 Gaboxadol 2007
Cystatin C reduces the in vitro formation of soluble Abeta1-42 oligomers and protofibrils Selenica ML, Wang X, Ostergaard Pedersen L, Westlind Danielsson A, Grubb A Scandinavian Journal of Clinical and Laboratory Investigation 2007;67 (2):179-190 - 2007
Probing the Pharmacophore of Ginkgolides as Glycine Receptor Antagonists Jensen AA, Begum Nasreen, Vogensen SB, Knapp Kolja M, Gundertofte K, Dzyuba Sergei V, Ishii Hideki, Nakanishi Koji, Kristiansen U, Stromgaard K Journal of Medicinal Chemistry 2007;50(7):1610-1617 - 2007
Effect of short-term treatment with gaboxadol on sleep maintenance and initiation in patients with primary insomnia Deacon S, Staner L, Staner C, Legters A, Loft H, Lundahl J Sleep 2007;30(3):281-287 Gaboxadol 2007

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